Scar Treatment After Skin Trauma, Burn or Injury

The human body can sustain a variety of injuries, including penetrating trauma, burn trauma and blunt trauma. All of these insults set into motion an orderly sequence of events that are involved in the healing response, in which the normal functional tissue (skin) is replaced by connective tissue (scar) and the healing response is characterized by the movement of specialized cells into the wound site.

Healing is the complex and dynamic process that results in the restoration of anatomical continuity and function. There are four basic responses that can occur following an injury:

Regeneration (exact replacement)
Regeneration is the elegant process that occurs when there is loss of structure and function but the organism has the sophisticated capacity to replace that structure by replacing exactly what was there before the injury. Lower forms of life, such as the salamander and crab, can regenerate tissues in this manner. As man has evolved, we have lost this capacity and can only replace a limited amount of damaged tissues by the process of regeneration.

Normal repair (reestablished equilibrium)
Normal repair is the response where there is a re-established equilibrium between scar formation and scar remodeling. This is the typical response that most humans experience following injury. The pathological responses to tissue injury stand in sharp contrast to the normal repair response.

Excessive healing (fibrosis and contractures)
In excessive healing there is too much deposition of connective tissue that results in altered structure and, thus, loss of function. Fibrosis, strictures, adhesions and contractures are examples of excessive healing. Keloids and hypertrophic scars in the skin are examples of fibrosis. Contraction is part of the normal process of healing but if excessive, it becomes pathologic and is known as a contracture.

Deficient healing (chronic ulcers)
Deficient healing is the opposite of fibrosis; it exists when there is insufficient deposition of connective tissue matrix and the tissue is weakened to the point where it can fall apart. Chronic non-healing ulcers are examples of deficient healing.

Scar Healing Process

When an injury occur a movement of different cells comes immediately and the complex healing process just begins in the moment it's happened.

When we say "complex" we really do not do justice in conveying the intricately and coordinated degree of orchestration that occurs between the many cells, organs and products of the immune system, which do such a masterful job of maintaining our biological, health-full integrity.

Platelets and inflammatory cells are the first cells to arrive at the site of injury and they provide key functions and “signals” needed for the influx of connective tissue cells and a new blood supply. This phase is named inflammatory phase. The signs have been well recognized since ancient times: rubor (redness), calor (heat), tumor (swelling) and dolor (pain).

The presence of wound macrophages is a marker that the inflammatory phase is nearing an end and the proliferative phase is beginning. Lymphocytes (white blood cell that helps the body fight infection) come into the wound area at a later stage.

As the Proliferative phase progresses the predominant cell in the wound site is the fibroblast. This cells originate in the mesoderm that gives rise to the connective tissue of the body, blood vessels, and lymph vessels and is responsible for producing the new matrix needed to restore structure and function to the injured tissue. Fibroblasts attach to the cables of the provisional fibrin matrix and begin to produce collagen.

Collagen is the most abundant protein in the animal kingdom, accounting for 30% of the total protein in the human body. In normal tissues collagen provides strength, stability and structure. Collagen is needed to repair the defect and restore anatomic structure and function. If too much collagen is deposited in the wound site, normal anatomical structure is lost, function is compromised and fibrosis occurs.

The collagen released into the extracellular space undergoes further processing by opening of the procollagen N and C-terminal peptides. In the extra-cellular spaces an important enzyme, lysyl oxidase, acts on the collagen to form stable cross-links. As the collagen matures and becomes older, more and more of these intramolecular and intermolecular cross-links are placed in the molecules. This important cross-linking step gives collagen its strength and stability over time.

In summary, the normal healing cascade begins with an orderly process of hemostasis and fibrin deposition, which leads to an inflammatory cell cascade, characterized by neutrophils, macrophages and lymphocytes within the tissue. This is followed by attraction and proliferation of fibroblasts and collagen deposition, and finally remodeling by collagen cross-linking and scar maturation. Despite this orderly sequence of events responsible for normal wound healing, pathologic responses leading to fibrosis or chronic ulcers may occur if any part of the healing sequence is altered.

Fibrosis: Abnormal Skin reaction to an injury

Fibrosis can be defined as the replacement of the normal structural elements of the tissue by distorted, non-functional and excessive accumulation of scar tissue. This is perhaps the most significant biological marker for fibrosis. Many clinical problems are associated with excessive scar formation for example, keloids and hypertrophic scars.

BIO SKIN CARE™ Cream helps to REGULATE collagen deposition and the orderly process of biological healing.

BIO SKIN CARE™ is a natural product that can help your body regulate the levels of collagen, the most important component of the skin regeneration process. BIO SKIN CARE™ main component is the natural secretions from a Chilean land snail (Helix Aspersa Muller), the same they use to quickly repair their own skin and shell when damaged. It is a viscose liquid that is made into an odorless white cream with no alien or synthetic chemicals.

What is unique about the proteins and glycosaminoglycans (complex sugar structures) in the snail secretions is their high bio-availability and signaling function, which allows them to minimize scar tissue formation as well as reversing existing scar tissues.

A natural cosmetic product, not a drug, pharmaceutical, or product aimed to cure a disease.

Topical application of the cream on skin wounds and scars has shown to decrease dermal fibroblast proliferation, and prevent and reduce keloid and hyperthropic scars.

Unlike harsh chemicals and physical processing typically used to produce protein supplements, which unfortunately denatures (destroys) the natural configuration of proteins yielding something that is not completely absorbed and utilized by the human body.

The topical application of BIO SKIN CARE™ on your skin is also a potent message to your body. It will know it is being properly taken care off, so it will not need to over-react forming those abnormal thick scar tissues.

Analysis of the mucin has determined that it contains activators of skin growth factors and antimicrobial peptides. Also present are natural anti-inflammatory and immune modulating proteins, glycoproteins, glycosaminoglycans that tightly binds divalent cations, such as copper (II), and acharan sulfate glycosaminoglycan (GAG), as a protein-free polysaccharide.

The Bioactive Ingredients in BIO SKIN CARE™ Act As:

(1) Regulators of enzyme activity
(2) Regulators of neurite outgrowth
(3) Anti-inflammatory agents that limits oxidative damage after tissue injury;
(4) Stabilizers, cofactors, and/or co-receptors for
(4a) proteins produced by the human body that enable cells to communicate and effectively coordinate activities between one another (growth factors)
(4b) intracellular messenger molecules whose major function is to attract immune cells to sites of infection, and
(4c) as regulatory proteins released by cells of the immune system that act as intercellular mediators in the generation of an immune response (cytokines).

In a nutshell: BIO SKIN CARE™ cream helps your skin regenerate itself! It is also anti-microbial, thereby helping to prevent skin infections. Is there nothing like it! And you can use it for treating a wide variety of skin problems: wounds, burns, sunburns, and rashes, cracked and dry skin. It works great on post-surgical scars. It has been used on age lines, age spots, abrasions, acne, athlete's foot, boils, chilblains, diabetic sores, diaper rash, infected nails, insect bites/stings, skin allergies, skin ulcers and stretch marks with incredible results. It is just excellent for helping the skin to repair itself. Wounds heal with minimal scarring. It also helps shrink old scars